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pentobarbital will lower the extent or effect of fosamprenavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will lessen the extent or result of irinotecan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.pentobarbital will reduce the level or outcome of ombitasvir/pari